Circulation 11-9-2004;110(19):3011-3016. Rev Neurol (Paris) 1989;145(12):842-850. Fogagnolo, P., Sacchi, M., Ceresara, G., Paderni, R., Lapadula, P., Orzalesi, N., and Rossetti, L. The effects of topical coenzyme Q10 and vitamin E D-alpha-tocopheryl polyethylene glycol 1000 succinate after cataract surgery: a clinical and in vivo confocal study. View abstract. View abstract. Aoki S and Yamaguchi K. [Clinical experiences in use of cinnarizine and CoQ10 for treatment of sensorineural tinnitus]. View abstract. Sander S, Coleman CI, Patel AA, et al. 2012;4:CD004426. Ogasahara, S., Nishikawa, Y., Yorifuji, S., Soga, F., Nakamura, Y., Takahashi, M., Hashimoto, S., Kono, N., and Tarui, S. Treatment of Kearns-Sayre syndrome with coenzyme Q10. Some research in Chinese women suggests that having low blood levels of coenzyme Q10 is linked to an increased risk of breast cancer. View abstract. J Strength Cond.Res 2010;24(1):97-102. Coenzyme Q10 is often sold as an herbal supplement. Do not use this product without medical advice if you are breast-feeding a baby. Acta Otolaryngol. Invest New Drugs 2001;19:81-3. 2010;29(1):21-37. View abstract. A single blind placebo-controlled and randomized clinical study [abstract]. Am.J.Clin.Nutr. Safarinejad MR. Efficacy of coenzyme Q-10 on semen parameters, sperm function and reproductive hormones in infertile men. Coenzyme Q10 is a vitamin-like substance that is made naturally in the body. 2003;12:135-41. Int J Cardiol. Effect of coenzyme Q10 on ischemia-induced ST-segment depression: a double-blind, placebo-controlled, crossover study. Free Radic.Res 1998;29(1):85-92. Kim, Y., Sawada, Y., Fujiwara, G., Chiba, H., and Nishimura, T. Therapeutic effect of co-enzyme Q10 on idiopathic dilated cardiomyopathy: assessment by iodine-123 labelled 15-(p-iodophenyl)- 3(R,S)-methylpentadecanoic acid myocardial single-photon emission tomography. View abstract. High Blood Press Cardiovasc Prev. Folkers K, Langsjoen P, Willis R, et al. Amsterdam: Elsevier Science;1991. Open label trial of coenzyme Q10 as a migraine preventive. View abstract. Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent Migraine. Can.Fam.Physician 2008;54(11):1529-1533. [Application of coenzyme Q(10) in combination therapy of arterial hypertension]. Voronkova, K. V. and Meleshkov, M. N. [Noben (idebenone) in the treatment of dementia and memory impairment without dementia]. View abstract. 2008;8(4):310-319. 2008;7(1):60-67. Nishino, M., Usami, M., Sugimura, S., and Yoshizaki, S. [Case of drug-induced pneumonitis associated with a dietary supplement containing CoQ10]. Curr Opin.Chem Biol. First Conference of the International Coenzyme Q10 Association 1998; Scarlato, G., Bresolin, N., Moroni, I., Doriguzzi, C., Castelli, E., Comi, G., Angelini, C., and Carenzi, A. Multicenter trial with ubidecarenone: treatment of 44 patients with mitochondrial myopathies. Naylor CD, O'Rourke K, Detsky AS, Baker JP. 2010;35(6):486-489. Protective action of L-carnitine and coenzyme Q10 against hepatic triglyceride infiltration induced by hyperbaric oxygen and ethanol. Effectiveness of coenzyme Q10 in prophylactic treatment of migraine headache: an open-label, add-on, controlled trial. Clin Ther. Effect of coenzyme Q10 on essential arterial hypertension. Role of coenzyme Q10 in chronic heart failure, angina, and hypertension. View abstract. J Basic Clin Physiol Pharmacol. Neurotherapeutics. N.Z.Med J 10-30-2009;122(1305):74-79. Int J Sports Med 1999;20(3):154-158. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Adequate vitamin D (vit D) levels have been shown to reduce vascular smooth muscle contraction and to increase arterial compliance, which may be beneficial in hypertension. A soccer match's ability to enhance lymphocyte capability to produce ROS and induce oxidative damage. Cordero, M. D., de, Miguel M., Moreno Fernandez, A. M., Carmona Lopez, I. M., Garrido, Maraver J., Cotan, D., Gomez, Izquierdo L., Bonal, P., Campa, F., Bullon, P., Navas, P., and Sanchez Alcazar, J. Acta Ophthalmol. View abstract. Mizuno, M., Quistorff, B., Theorell, H., Theorell, M., and Chance, B. Langsjoen, P. H., Folkers, K., Lyson, K., Muratsu, K., Lyson, T., and Langsjoen, P. Pronounced increase of survival of patients with cardiomyopathy when treated with coenzyme Q10 and conventional therapy. View abstract. 2011;(12):CD008150. Pandolfo, M. Introduction. BBelardinelli R, Mucaj A, Lacalaprice F, et al. This medicine is also known as Coenzima, Ubidcarenone, Ubidécarénone, and Ubiquinol. Int J Cardiol 2003;88:101-2. Neuromuscul.Disord. Weis M, Mortensen SA, Rassing MR, et al. View abstract. View abstract. 2010;67(8):941-947. Forgionne, G. A. Eur Neurol 1997;37:212-8. Schardt F, Welzel D, Scheiss W, and et al. Coenzyme Q10 in the treatment of corneal edema in Kearns-Sayre: is there an application in Fuchs endothelial corneal dystrophy? Biochem Biophys Res Commun 1991;176:786-91. Muscle pain caused by statin drugs (statin-induced myalgia). Taking coenzyme Q10 does not seem to improve mental function in people with Alzheimer disease. J Am Coll Nutr. Balercia G, Arnaldi G, Lucarelli G, and et al. 2006;79(6):1125-1129. View abstract. Inability to become pregnant within a year of trying to conceive (infertility). Effect of topical application of coenzyme Q10 on adult periodontitis. Mazzola C, Guffanti EE, Vaccarella A, and et al. Am J Hum.Genet. View abstract. The effect of pravastatin and atorvastatin on coenzyme Q10. Soongswang J, Sangtawesin C, Durongpisitkul K, et al. Does coenzyme Q. Folkers K, Hanioka T, Xia LJ, et al. View abstract. Rinsho Shinkeigaku 2005;45(6):416-421. Diabet Med 1999;16:312-8. Biofactors 2008;32:145-9. Hirano, M., Quinzii, C. M., and DiMauro, S. Restoring balance to ataxia with coenzyme Q10 deficiency. Sinatra, S. T. Metabolic cardiology: an integrative strategy in the treatment of congestive heart failure. Ogasahara, S., Yorifuji, S., Nishikawa, Y., Takahashi, M., Wada, K., Hazama, T., Nakamura, Y., Hashimoto, S., Kono, N., and Tarui, S. Improvement of abnormal pyruvate metabolism and cardiac conduction defect with coenzyme Q10 in Kearns-Sayre syndrome. The Use of Vitamins and Coenzyme Q10 for the Treatment of Vascular Occlusion Diseases Affecting the Retina. Ideggyogy.Sz 1-30-2009;62(1-2):25-34. View abstract. Am Heart J 2011;161(3):639-645. Weston SB, Zhou S, Weatherby RP, Robson SJ. 2016;19(3):138-43. doi: 10.1179/1476830515Y.0000000002. View abstract. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Coenzyme Q10 only for the indication prescribed. 2018 Jan;28(1):25-31. View abstract. 2015;19:275. doi: 10.1186/s13054-015-0989-3. Mol Aspects Med 1997;18 Suppl:S213-9. Kishi H, Kishi T, Folkers K. Bioenergetics in clinical medicine. 1-18-2010;469(1):159-163. Rev.Neurol. Hauser, R. A. View abstract. J Clin Psychiatry 2005;66(5):625-632. Nutr Metab Cardiovasc.Dis 2010;20(2):133-139. A hormonal disorder that causes enlarged ovaries with cysts (polycystic ovary syndrome or PCOS). 2009;256 Suppl 1:42-45. Mol Aspects Med 1997;18 Suppl:S145-51. Weakened and enlarged heart (dilated cardiomyopathy). 1993;71(8 Suppl):S129-33. Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. The impact of two doses of coenzyme Q10 on semen parameters and antioxidant status in men with idiopathic oligoasthenoteratozoospermia. View abstract. Bioenergetics in clinical medicine. Lopez, L. C., Schuelke, M., Quinzii, C. M., Kanki, T., Rodenburg, R. J., Naini, A., DiMauro, S., and Hirano, M. Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations. Reid, M. S., Casadonte, P., Baker, S., Sanfilipo, M., Braunstein, D., Hitzemann, R., Montgomery, A., Majewska, D., Robinson, J., and Rotrosen, J. Ramelli, G. P., Gallati, S., Weis, J., Krahenbuhl, S., and Burgunder, J. M. Point mutation tRNA(Ser(UCN)) in a child with hearing loss and myoclonus epilepsy. View abstract. 1987;234(1):62-63. Florou P, Anagnostis P, Theocharis P, Chourdakis M, Goulis DG. Effects of coenzyme Q10 on arterial stiffness, metabolic parameters, and fatigue in obese subjects: a double-blind randomized controlled study. Tsuyama, Y., Adachi-Usami, E., and Takeda, N. A case of Kearns-Shy syndrome with later onset. Biochem Biophys Res Commun 1994;199:1504-8. 8-1-2008;128(1):e43-e45. Rev Neurol. Ann.Neurol. Taylor BA, Lorson L, White CM, Thompson PD. Efficacy of eyedrops containing cross-linked hyaluronic acid and coenzyme Q10 in treating patients with mild to moderate dry eye. However, it doesn't seem to benefit people with normal coenzyme Q10 levels. View abstract. Nutrients 2018;10(11). View abstract. Mol.Aspects Med 1994;15 Suppl:s155-s63. Clin Biochem 2011;44(8-9):669-674. J Clin Endocrinol.Metab 2006;91(12):4737-4742. Bloomer, R. J., Canale, R. E., McCarthy, C. G., and Farney, T. M. Impact of oral ubiquinol on blood oxidative stress and exercise performance. Drug Saf 2009;32(8):649-661. Bovine cartilage, coenzyme Q10, and wheat grass therapy for primary peritoneal cancer. J Neurol 1998;245:681-5. View abstract. Shults, C. W., Haas, R. H., and Beal, M. F. A possible role of coenzyme Q10 in the etiology and treatment of Parkinson's disease. In: Yamamura Y, Folkers K, Ito Y (eds). PLoS One. Clin Neuropharmacol 2004;27:187-91. View abstract. Laaksonen, R., Fogelholm, M., Himberg, J. J., Laakso, J., and Salorinne, Y. Ubiquinone supplementation and exercise capacity in trained young and older men. Curr Opin Neurol 1998;11:193-7. Rastogi SS, Singh RB, and Shukla PK. Hershey AD, Powers SW, Vockell AB, et al. Increase in the oxidized/total coenzyme Q-10 ratio in the cerebrospinal fluid of Alzheimer's disease patients. View abstract. Increased mitochondrial oxidative damage in patients with sporadic amyotrophic lateral sclerosis. Cochrane Database Syst.Rev. Zeppilli P, Merlino B De Luca A Palmieri V Santini C Vannicelli R La Rosa Gangi M Cacese R Cameli S Servidei S Ricci E Silvestri G Lippa S Oradei A Littarru GP. 2010;91(7):1044-1050. View abstract. Bipolar disorder. View abstract. Orlando P, Silvestri S, Galeazzi R, et al. Gold, R., Seibel, P., Reinelt, G., Schindler, R., Landwehr, P., Beck, A., and Reichmann, H. Phosphorus magnetic resonance spectroscopy in the evaluation of mitochondrial myopathies: results of a 6-month therapy study with coenzyme Q. Eur.Neurol. J Clin Pharm Ther. Am Heart Hosp.J 2006;4(4):301-302. J Strength Cond.Res 2009;23(8):2326-2330. However, there is some early evidence that taking coenzyme Q10 by mouth might be helpful. 2009;23(2):144-145. 2011;34(4):211-217. Gutzmann, H., Kuhl, K. P., Hadler, D., and Rapp, M. A. B., Navas, P., DiMauro, S., and Montini, G. Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition. Balercia, G., Mancini, A., Paggi, F., Tiano, L., Pontecorvi, A., Boscaro, M., Lenzi, A., and Littarru, G. P. Coenzyme Q10 and male infertility. Lee YJ, Cho WJ, Kim JK, Lee DC. View abstract. View abstract. Rev Med Interne 1992;13(5):381-383. 2018 Apr 11;13(4):e0193120. J Am Acad Dermatol 2006;54(2):234-241. Ubidecarenone in the treatment of mitochondrial myopathies: a multi-center double-blind trial. 2015 Jun;35(3):338-40. doi: 10.1097/JCP.0000000000000326. 2008;26(4):371-378. Langsjoen, P. H. and Langsjoen, A. M. Overview of the use of CoQ10 in cardiovascular disease. View abstract. Mol Aspects Med 1994;15 Suppl:s257-63. If one is going to make an evolutionary argument for what a “natural” vitamin D level may be, how about getting vitamin D … Eur.J Clin Invest 2009;39(1):23-30. View abstract. US Pharm 2000;25:28-41. 2014;5(3-4):187-97. 2011;21(6):396-405. View abstract. Research also has shown that Coenzyme Q10 is not likely to be effective in increasing athletic performance. View abstract. J Thorac.Cardiovasc.Surg. View abstract. Diabetes. 2012;69(8):978-83. Clinical response of myelodysplastic syndromes patients to treatment with coenzyme Q10. 2016 Mar 3;3:CD007435. Mol Cell Biochem 2003;246:75-82. Parashos, S. A., Swearingen, C. J., Biglan, K. M., Bodis-Wollner, I., Liang, G. S., Ross, G. W., Tilley, B. C., and Shulman, L. M. Determinants of the timing of symptomatic treatment in early Parkinson disease: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) Experience. 2012;188(2):526-31. However, not all research has shown benefit. Res Commun.Chem Pathol.Pharmacol 1981;31(1):129-140. In: Folkers K and Yamura Y. Biomedical and Clinical Aspects of Coenzyme Q. Amsterdam: Elsevier Science Publications;1984. View abstract. View abstract. J Cyst.Fibros. View abstract. Okamura, T., Sunamori, M., Amano, J., Hirooka, Y., Ozeki, M., Tanaka, A., and Suzuki, A. Ischemic heart lesions during chronic heart failure homocysteine to the amino acid methionine, the oxidation of …. G tolerance associated with a load-induced cardiac dysfunction: double blind, placebo controlled.! Nicieza J, Lepies P, Filipiak KJ, Pella D, R... Whether ubiquinone passes into breast milk or if it could harm a nursing baby and physical development in and! K. P., Majamaa, K., Furuta, I., and coenzyme Q10 treatment in heart. Lee DC on stress-induced cardiac dysfunction: double blind, placebo controlled of. And Halliwell, B and Beal, M., Emmett, P. H. and,! 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